Express News Service
NEW DELHI: At a time when the country is facing a shortage of Remdesivir, scientists have investigated 61 antiviral drugs and found a combination that has superior anti-SARS-CoV-2 potential.
A team of scientists from the Biochemical Sciences Division, CSIR-National Chemical Laboratory, India Academy of Scientific and Innovative Research (AcSIR), Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, and INTOX Private Limited, Pune worked on the efficacy of drug repurposing for treating Covid-19.
“Our analysis suggested Sofosbuvir in combination with Ledipasvir and Daclatasvir as potential therapeutic agents for SARS-CoV-2. The combined score suggests that these combinations have superior anti-SARS-CoV-2 potential than Remdesivir and other investigational drugs,” they said in a paper published in Current Science.
They said the present work provides a rationale-based approach to select drugs with possible…